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KMID : 0380020070220060414
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Korean Journal of Biotechnology and Bioengineering
2007 Volume.22 No. 6 p.414 ~ p.420
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Toxicity Monitoring and Assessment of Nanoparticles Using Bacteria
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Lee Jung-Ill
Sang Byoung-In
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Abstract
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Nanomaterials have been applied to various fields due to their advantageous characteristics such as high surface area, rapid diffusion, high specific surface areas, reactivity in liquid or gas phase, and a size close to biomacromolecules. Up to date, increased manufacturing and frequently use of the materials, however, revoke people’s concerns on their hazard impact including toxicity the materials. Many research groups have carried out different protocols to evaluate toxic effects of nanomaterilas on different organisms, and consequently, nanomaterials are known to cytotoxicity. In this paper, we reviewed some of the most reports on toxic effects of several nanoparticles specifically on bacteria. There are numbers of reports focused on antibacterial effect of nanoparticles based on bacterial cell viability. Therefore, the application of each nanomaterial should be concerned with its toxicity and its toxic effect should be evaluated in terms of concentrations and sizes of the nanomaterials used, prior to use of a nanomaterial.
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KEYWORD
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Nanoparticles, nanoparticles toxicity, antibacterial effect, toxic mechanism
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